EINE ÜBERPRüFUNG DER METHADONTABLETTEN ZUR SCHMERZBEHANDLUNG

Mutagenesis – There are several published reports on the potential genetic toxicity of methadone. Methadone tested negative in tests for chromosome breakage and disjunction and sex-linked recessive lethal gene mutations in germ cells of Drosophila using feeding and injection procedures.When treating pain, methadone given on a fixed-dose schedule